SAFETY DATA SHEET
Kovac's Reagent
1. IDENTIFICATION
Product Identifiers
Product Name:
Kovac's reagent
Other Names:
Indole reagent
Product Number(s):
AKOVC-20
CAS Number:
-
Recommended use of the chemical and restriction on use
Laboratory use.
Used in hospital and pathology laboratories only.
Used in hospital and pathology laboratories only.
Company Details
ProSciTech Pty Ltd
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
Emergency Contact Details
ProSciTech Pty Ltd
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
11 Carlton Street
KIRWAN QLD 4817
Australia(07) 4773 9444www.proscitech.com
2. HAZARDS IDENTIFICATION
Classification of the substance or mixture
Classified as Hazardous according to the Globally Harmonised System of Classification and Labelling of Chemicals (GHS) and Safe Work Australia criteria.
Label Elements
Signal Words
Warning
Hazard Statement(s)
H226 Flammable liquid and vapour.
H302 Harmful if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
H302 Harmful if swallowed.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
Precautionary Statement(s)
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P241 Use explosion-proof electrical/ventilating/lighting/equipment.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P240 Ground/bond container and receiving equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P321 Specific treatment (see on this label).
P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P313 If skin irritation occurs: Get medical advice/attention.
P337+P313 If eye irritation persists: Get medical advice/attention.
P330 Rinse mouth.
P370+P378 In case of fire: Use for extinction: CO₂, powder or water spray.
P362+P364 Take off contaminated clothing and wash it before reuse.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container in accordance with local/regulations.
P241 Use explosion-proof electrical/ventilating/lighting/equipment.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P240 Ground/bond container and receiving equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P264 Wash hands thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P321 Specific treatment (see on this label).
P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P313 If skin irritation occurs: Get medical advice/attention.
P337+P313 If eye irritation persists: Get medical advice/attention.
P330 Rinse mouth.
P370+P378 In case of fire: Use for extinction: CO₂, powder or water spray.
P362+P364 Take off contaminated clothing and wash it before reuse.
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container in accordance with local/regulations.
Primary route(s) of entry
Not available.
Human Health
Inhalation:
May be harmful if inhalted. May cause respiratory irritation leading to headache, cough, dizziness incoordination and chest pains.
Ingestion:
Harmful if swallowed. May cause irritation of mouth, throat and stomach, mucous build up and stomach pain.
Eyes:
Causes serious eye irritation, stinging, tearing and blurred vision. May cause eye damage.
Skin:
Causes skin irritation, itchiness and redness.
Environment
Not available.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Name
CAS No.
Content (w/w)
Classification
3-methylbutan-1-ol
123-51-3
72.5%
Flam. Liq. 3, H226; Acute Tox. 3, H301
Hydrochloric acid
7647-01-0
22.5%
Skin Corr. 1B, H314;STOT SE 3, H335
4-dimethylaminobenzaldehyde
100-10-7
5%
Acute Tox. 3, H301
4. FIRST AID MEASURES
Ingestion
If swallowed, do not induce vomiting. Never give anything by mouth to an unconscious person. Seek immediate medical attention.
Inhalation
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Seek medical attention if breathing problems develop. Do not use mouth-to-mouth method, use an alternative method or a proper respiratory device.
Skin Contact
In case of skin contact, immediately remove contaminated clothing and wash affected areas with water and soap. Seek medical attention if symptoms persist.
Eye Contact
In case of eye contact, hold eyelids open and rinse with water for at least 15 minutes. Seek immediate medical attention.
Other Information
No further relevant information available.
5. FIREFIGHTING MEASURES
Suitable extinguishing equipment
Foam, dry chemical or carbon dioxide.
HAZCHEM
Not available.
Special protective equipment and precautions for fire fighters
6. ACCIDENTAL RELEASE MEASURES
Personal precautions, protective equipment and emergency procedures
Wear appropriate respiratory protection and protective clothing. Evacuate all non-essential personnel from affected area. Do not breathe vapours. Ensure adequate ventilation. Extinguish all sources of ignition. Avoid sparks and open flames. No smoking.
Environmental precautions
In the event of a major spill, prevent spillage from entering drains or water courses.
Methods and materials for containment and clean up
Stop leak if safe to do so and absorb spill with sand, earth, vermiculite or some other absorbent material. Do not use sawdust. Collect the spilled material and place into a suitable container for disposal. Blanket the spill with foam or use water spray to disperse vapours. Use only non-sparking tools.
7. HANDLING AND STORAGE
Precautions for safe handling
Use of safe work practices are recommended to avoid eye or skin contact and inhalation of vapours. Use only outdoors or in a well-ventilated area.
Take precautionary measures against static discharge. Food, beverages and tobacco products should not be stored or consumed where this material is in use. Always wash hands before smoking, eating, drinking or using the toilet. Wash contaminated clothing and other protective equipment before storage or re-use. Provide eyewash fountains and safety showers in close proximity to points of potential exposure.
Take precautionary measures against static discharge. Food, beverages and tobacco products should not be stored or consumed where this material is in use. Always wash hands before smoking, eating, drinking or using the toilet. Wash contaminated clothing and other protective equipment before storage or re-use. Provide eyewash fountains and safety showers in close proximity to points of potential exposure.
Conditions for safe storage
8. EXPOSURE CONTROLS/PERSONAL PROTECTION
Exposure Standards
Material
TWA ppm
TWA mg/m3
STEL ppm
STEL mg/m3
3-methylbutan-1-ol
100 ppm
361 mg/m³
125 ppm
452 mg/m³
Hydrochloric acid
5 ppm
7.5 mg/m³
5 ppm
7.5 mg/m³
Engineering controls
Provide sufficient mechanical (general and/or local exhaust) ventilation to maintain exposure below the limits.
Personal protective equipment
Eye and face protection
Eye and face protectors for protection against splashing materials or liquids. See Australian/New Zealand Standard AS/NZS 1337 for more information.
Skin protection
PVC, nitrile, neoprene or rubber gloves. See Australian/New Zealand Standard AS/NZS 2161 for more information. When selecting gloves for use against certain chemicals, the degradation resistance, permeation rate and permeation breakthrough time should be considered.
Occupational protective clothing (depending on conditions in which it has to be used, in particular as regards the period for which it is worn, which shall be determined on the basis of the seriousness of the risk, the frequency of exposure to the risk, the characteristics of the workstation of each worker and the performance of the protective clothing). See Australian/New Zealand Standard AS/NZS 4501 for more information.
Occupational protective clothing (depending on conditions in which it has to be used, in particular as regards the period for which it is worn, which shall be determined on the basis of the seriousness of the risk, the frequency of exposure to the risk, the characteristics of the workstation of each worker and the performance of the protective clothing). See Australian/New Zealand Standard AS/NZS 4501 for more information.
Body protection
No information available.
Respiratory protection
When vapours approach the exposure standards then the use of a half-face organic vapour respirator with dust/mist filter is recommended.
When vapours exceed the exposure standards, the use of an positive pressure demand self-contained or airline breathing apparatus is recommended. Filter capacity and respirator type depends on exposure levels. If entering spaces where the airborne concentration of a contaminant is unknown then the use of a selfcontained breathing apparatus (SCBA) with positive pressure air supply is recommended. See Australian Standards AS/NZS 1715 and 1716 for more information.
When vapours exceed the exposure standards, the use of an positive pressure demand self-contained or airline breathing apparatus is recommended. Filter capacity and respirator type depends on exposure levels. If entering spaces where the airborne concentration of a contaminant is unknown then the use of a selfcontained breathing apparatus (SCBA) with positive pressure air supply is recommended. See Australian Standards AS/NZS 1715 and 1716 for more information.
9. PHYSICAL AND CHEMICAL PROPERTIES
General information
Appearance
Liquid straw colour
Odour
Mild pleasant odour.
pH
Not available.
Vapour Pressure
at 20 °C: 33 hPa
Density
Not available.
Boiling Point
131 °C
Melting Point
-117 °C
Solubility
Soluble in water 30.6 g/L
Specific Gravity of Density
Not available.
Flash Point
42 °C
Flammable (Explosive) Limits
No information available.
Ignition Temperature
Not applicable.
Formula
Not available.
10. STABILITY AND REACTIVITY
Reactivity
No further relevant information available.
Chemical stability
Stable at ambient temperature and under normal conditions of use.
Possibility of hazardous reactions
Hazardous polymerisation will not occur.
Conditions to avoid
Heat, sparks, open flames and other sources of ignition.
Incompatible materials
Strong oxidising agents and alkalies.
11. TOXICOLOGICAL INFORMATION
Acute effects
Repeated or prolonged skin exposure may cause dermatitis. Prolonged or repeated exposure may cause irreversible damage to health, lung damage or death.
Eye contact
Causes serious eye irritation, stinging, tearing and blurred vision. May cause eye damage.
Skin contact
Causes skin irritation, itchiness and redness.
Ingestion
Harmful if swallowed. May cause irritation of mouth, throat and stomach, mucous build up and stomach pain.
Inhalation
May be harmful if inhalted. May cause respiratory irritation leading to headache, cough, dizziness incoordination and chest pains.
Toxicity and irritation
LD??/LC?? Values Relevant for Classification:
123-51-3 3-methylbutan-1-ol
Oral LD?? 1300 mg/kg (rat)
Dermal LD?? 3212 mg/kg (rabbit)
7647-01-0 Hydrochloric acid
Oral LD?? 900 mg/kg (rabbit)
123-51-3 3-methylbutan-1-ol
Oral LD?? 1300 mg/kg (rat)
Dermal LD?? 3212 mg/kg (rabbit)
7647-01-0 Hydrochloric acid
Oral LD?? 900 mg/kg (rabbit)
12. ECOLOGICAL INFORMATION
Ecotoxicity
May cause long term adverse effects in the aquatic environment.
Persistence and degradability
No further relevant information available.
Bioaccumulative potential
No further relevant information available.
Other adverse effects
No further relevant information available.
13. DISPOSAL CONSIDERATIONS
General information
Dispose according to applicable local and state government regulations.
Special Precautions for Landfill or Incineration:
Please consult your state Land Waste Management Authority for more information.
Special Precautions for Landfill or Incineration:
Please consult your state Land Waste Management Authority for more information.
14. TRANSPORT INFORMATION
ADG label required
HAZCHEM
Not available.
UN Number
UN2924
Proper shipping name
FLAMMABLE LIQUID, CORROSIVE, N.O.S. (PENTANOLS, 4-dimethylaminobenzaldehyde.
Transport hazard class
3 F
Packing group
II
Environmental hazard
No information available.
Special precautions for users
EMS Number: F-E,S-C
Hazchem Code: .3WE
Special Provisions: 274
Hazchem Code: .3WE
Special Provisions: 274
Additional information
Packagings & IBCs - Packing Instruction: P001, IBC02 Packagings & IBCs - Special Packing Provisions: No information available
Portable Tanks & Bulk Containers - Instructions: T11 Portable Tanks & Bulk Containers - Special Provisions: TP2, TP27
Portable Tanks & Bulk Containers - Instructions: T11 Portable Tanks & Bulk Containers - Special Provisions: TP2, TP27
15. REGULATORY INFORMATION
Poisons Schedule Number
Poisons Schedule: 6
Other Information
No further relevant information available.
16. OTHER INFORMATION
SDS preparation date
6 October 2021
Comments
This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship.
This Safety Data Sheet (SDS) has been prepared in compliance with the Preparation of Safety Data Sheets for Hazardous Chemicals Code of Practice February 2016. It is the user's responsibility to determine the suitability of this information for adoption of necessary safety precautions. The information published in this SDS has been compiled from the publications listed in Section 16: to the best of our ability and knowledge these publications are considered accurate. We reserve the right to revise Safety Data Sheets as new information becomes available. Copies may be made for non-profit use.